SQUALAMINE LACTATE

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 4WE915J1KX

Structure
InChI Key ZPYIELFRIYUVQP-BHBJEIPNSA-N
Smile CC(C)[C@@H](CC[C@@H](C)[C@H]1CC[C@H]2[C@H]3[C@H](CC[C@@]21C)[C@@]1(C)CC[C@H](NCCCNCCCCN)C[C@@H]1C[C@H]3O)OS(=O)(=O)O.C[C@H](O)C(=O)O.O
InChI
InChI=1S/C34H65N3O5S.C3H6O3.H2O/c1-23(2)31(42-43(39,40)41)12-9-24(3)27-10-11-28-32-29(14-16-34(27,28)5)33(4)15-13-26(21-25(33)22-30(32)38)37-20-8-19-36-18-7-6-17-35;1-2(4)3(5)6;/h23-32,36-38H,6-22,35H2,1-5H3,(H,39,40,41);2,4H,1H3,(H,5,6);1H2/t24-,25-,26+,27-,28+,29+,30-,31-,32+,33+,34-;2-;/m10./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C37H73N3O9S
Molecular Weight 736.07
AlogP 5.55
Hydrogen Bond Acceptor 7.0
Hydrogen Bond Donor 5.0
Number of Rotational Bond 16.0
Polar Surface Area 133.91
Molecular species ZWITTERION
Aromatic Rings 0.0
Heavy Atoms 43.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Sodium/hydrogen exchanger 3 inhibitor PubMed PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Macular Degeneration 3 D008268 ClinicalTrials
Macular Degeneration 3 D008268 ClinicalTrials
Diabetic Retinopathy 2 D003930 ClinicalTrials
Ovarian Neoplasms 2 D010051 ClinicalTrials
Prostatic Neoplasms, Castration-Resistant 2 D064129 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL3989689
FDA SRS 4WE915J1KX
PubChem 72734342
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