SULTHIAME

Search structure
Synonyms:
Status: Phase 1
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: I00Q766CZ2

Structure
InChI Key HMHVCUVYZFYAJI-UHFFFAOYSA-N
Smile NS(=O)(=O)c1ccc(N2CCCCS2(=O)=O)cc1
InChI
InChI=1S/C10H14N2O4S2/c11-18(15,16)10-5-3-9(4-6-10)12-7-1-2-8-17(12,13)14/h3-6H,1-2,7-8H2,(H2,11,15,16)

Physicochemical Descriptors

Property Name Value
Molecular Formula C10H14N2O4S2
Molecular Weight 290.37
AlogP 0.26
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 2.0
Polar Surface Area 97.54
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 18.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Carbonic anhydrase inhibitor PubMed
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Lyase
- - - 9-9 -
Enzyme
- - - 9-9 -

Indications

Mesh Heading Maximum Phase Mesh ID Reference

Related Entries

Scaffolds

Cross References

Resources Reference
CAS NUMBER 61-56-3
ChEBI 32171
ChEMBL CHEMBL328560
DrugBank DB08329
DrugCentral 2540
EPA CompTox DTXSID4023626
FDA SRS I00Q766CZ2
PDB OSP
PubChem 5356
SureChEMBL SCHEMBL38898
ZINC ZINC000000002119
CONTENTS