SX-682

Search structure
Synonyms:
Status: Phase 1
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: H5212R2DPM

Structure
InChI Key SDUDZBCEHIZMFZ-UHFFFAOYSA-N
Smile O=C(Nc1ccc(F)cc1)c1cnc(SCc2cc(OC(F)(F)F)ccc2B(O)O)nc1
InChI
InChI=1S/C19H14BF4N3O4S/c21-13-1-3-14(4-2-13)27-17(28)12-8-25-18(26-9-12)32-10-11-7-15(31-19(22,23)24)5-6-16(11)20(29)30/h1-9,29-30H,10H2,(H,27,28)

Physicochemical Descriptors

Property Name Value
Molecular Formula C19H14BF4N3O4S
Molecular Weight 467.21
AlogP None
Hydrogen Bond Acceptor None
Hydrogen Bond Donor None
Number of Rotational Bond None
Polar Surface Area None
Molecular species None
Aromatic Rings None
Heavy Atoms None

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Interleukin-8 receptors, CXCR1/CXCR2 inhibitor ClinicalTrials PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Melanoma 1 D008545 ClinicalTrials
Myelodysplastic Syndromes 1 D009190 ClinicalTrials
Carcinoma, Pancreatic Ductal 1 D021441 ClinicalTrials
Rectal Neoplasms 1 D012004 ClinicalTrials
Pulmonary Disease, Chronic Obstructive 1 D029424 ClinicalTrials

Cross References

Resources Reference
ChEMBL CHEMBL4297480
FDA SRS H5212R2DPM
Guide to Pharmacology 10165
PubChem 90467234
SureChEMBL SCHEMBL16436044
CONTENTS