| Synonyms: | |
| Status: | Phase 2 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | 1O8VSL798T |
Structure
| InChI Key | XVFJONKUSLSKSW-JTQLQIEISA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C10H15NO |
| Molecular Weight | 165.24 |
| AlogP | 0.73 |
| Hydrogen Bond Acceptor | 2.0 |
| Hydrogen Bond Donor | 0.0 |
| Number of Rotational Bond | 2.0 |
| Polar Surface Area | 12.47 |
| Molecular species | BASE |
| Aromatic Rings | 0.0 |
| Heavy Atoms | 12.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| AGONIST | Muscarinic acetylcholine receptor M1 agonist | PubMed |
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Membrane receptor
Family A G protein-coupled receptor
Small molecule receptor (family A GPCR)
Monoamine receptor
Acetylcholine receptor
|
2696 | - | - | - | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Alzheimer Disease | 2 | D000544 | ClinicalTrials |
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 147025-53-4 |
| ChEMBL | CHEMBL2111051 |
| DrugBank | DB12287 |
| EPA CompTox | DTXSID20163565 |
| FDA SRS | 1O8VSL798T |
| PubChem | 71792 |
| SureChEMBL | SCHEMBL195367 |
| ZINC | ZINC000001547638 |
CONTENTS