| Synonyms: | |
| Status: | Phase 2 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | Y3O05I09ZK |
Structure
| InChI Key | JFIWEPHGRUDAJN-DYUFWOLASA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C11H13N3O5 |
| Molecular Weight | 267.24 |
| AlogP | -2.56 |
| Hydrogen Bond Acceptor | 8.0 |
| Hydrogen Bond Donor | 4.0 |
| Number of Rotational Bond | 2.0 |
| Polar Surface Area | 130.83 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 1.0 |
| Heavy Atoms | 19.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| INHIBITOR | DNA-directed RNA polymerase III subunit RPC1 inhibitor | PubMed |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Head and Neck Neoplasms | 2 | D006258 | ClinicalTrials |
| Neoplasms | 1 | D009369 | ClinicalTrials |
Related Entries
MCS
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 180300-43-0 |
| ChEMBL | CHEMBL573352 |
| DrugBank | DB06656 |
| FDA SRS | Y3O05I09ZK |
| PubChem | 176885 |
| SureChEMBL | SCHEMBL543763 |
| ZINC | ZINC000003813525 |
CONTENTS