Synonyms: | |
Status: | Approved (2017) |
Entry Type: | Small molecule |
Molecule Category: | UNKNOWN Prodrug |
UNII: | 8G388563M7 |
InChI Key | MDSQOJYHHZBZKA-GBXCKJPGSA-N |
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Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C27H26ClF3N6O3 |
Molecular Weight | 574.99 |
AlogP | 4.99 |
Hydrogen Bond Acceptor | 9.0 |
Hydrogen Bond Donor | 2.0 |
Number of Rotational Bond | 9.0 |
Polar Surface Area | 131.17 |
Molecular species | NEUTRAL |
Aromatic Rings | 4.0 |
Heavy Atoms | 40.0 |
Action | Mechanism of Action | Reference |
---|---|---|
INHIBITOR | Tryptophan 5-hydroxylase inhibitor | FDA |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Carcinoid Heart Disease | 3 | D002275 | ClinicalTrials |
Neuroendocrine Tumors | 3 | D018358 | ClinicalTrials |
Malignant Carcinoid Syndrome | 2 | D008303 | ClinicalTrials |
Biliary Tract Neoplasms | 2 | D001661 | ClinicalTrials |
Liver Diseases | 1 | D008107 | ClinicalTrials |
Resources | Reference |
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CAS NUMBER | 1033805-22-9 |
ChEMBL | CHEMBL2105695 |
DrugBank | DB12095 |
DrugCentral | 5214 |
FDA SRS | 8G388563M7 |
Guide to Pharmacology | 9490 |
PubChem | 25181577 |
SureChEMBL | SCHEMBL610588 |
ZINC | ZINC000043205655 |