TEZAMPANEL

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 6XN50U405Y

Structure
InChI Key ZXFRFPSZAKNPQQ-YTWAJWBKSA-N
Smile O=C(O)[C@@H]1C[C@H]2C[C@@H](CCc3nn[nH]n3)CC[C@H]2CN1
InChI
InChI=1S/C13H21N5O2/c19-13(20)11-6-10-5-8(1-3-9(10)7-14-11)2-4-12-15-17-18-16-12/h8-11,14H,1-7H2,(H,19,20)(H,15,16,17,18)/t8-,9+,10-,11+/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C13H21N5O2
Molecular Weight 279.34
AlogP 0.61
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 4.0
Polar Surface Area 103.79
Molecular species ACID
Aromatic Rings 1.0
Heavy Atoms 20.0

Pharmacology

Action Mechanism of Action Reference
ANTAGONIST Glutamate receptor ionotropic AMPA antagonist

Indications

Mesh Heading Maximum Phase Reference
Migraine Disorders Phase 2 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
CAS NUMBER 154652-83-2
ChEMBL CHEMBL3989703
FDA SRS 6XN50U405Y
Guide to Pharmacology 4245
PubChem 127894
SureChEMBL SCHEMBL1649338
CAS NUMBER 154652-83-2
ChEMBL CHEMBL14935
DrugBank DB06354
FDA SRS 6XN50U405Y
Guide to Pharmacology 4245
PubChem 127894
SureChEMBL SCHEMBL1649338
ZINC ZINC000005134714
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