Synonyms: | |
Status: | Phase 2 |
Entry Type: | Small molecule |
Molecule Category: | UNKNOWN |
UNII: | GA36S2O9C2 |
InChI Key | ZXFRFPSZAKNPQQ-YTWAJWBKSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C13H21N5O2 |
Molecular Weight | 279.34 |
AlogP | 0.61 |
Hydrogen Bond Acceptor | 5.0 |
Hydrogen Bond Donor | 3.0 |
Number of Rotational Bond | 4.0 |
Polar Surface Area | 103.79 |
Molecular species | ACID |
Aromatic Rings | 1.0 |
Heavy Atoms | 20.0 |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Ion channel
Ligand-gated ion channel
Ionotropic glutamate receptor
AMPA receptor
|
- | 230-14000 | - | 2210-3200 | - | |
Ion channel
Ligand-gated ion channel
Ionotropic glutamate receptor
Kainate receptor
|
- | 230-31700 | - | 4160-4200 | 60 | |
Ion channel
Ligand-gated ion channel
Ionotropic glutamate receptor
NMDA receptor
|
- | 12100-61300 | - | - | 60 |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Migraine Disorders | 2 | D008881 | ClinicalTrials |
Resources | Reference |
---|---|
CAS NUMBER | 154652-83-2 |
ChEMBL | CHEMBL14935 |
DrugBank | DB06354 |
FDA SRS | GA36S2O9C2 |
Guide to Pharmacology | 4245 |
PubChem | 23725095 |
SureChEMBL | SCHEMBL1649338 |
ZINC | ZINC000005134714 |
CAS NUMBER | 154652-83-2 |
ChEMBL | CHEMBL3989703 |
FDA SRS | 6XN50U405Y |
Guide to Pharmacology | 4245 |
PubChem | 23725095 |