TINOSTAMUSTINE

Search structure
Synonyms:
Status: Phase 1
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 29DKI2H2NY

Structure
InChI Key GISXTRIGVCKQBX-UHFFFAOYSA-N
Smile Cn1c(CCCCCCC(=O)NO)nc2cc(N(CCCl)CCCl)ccc21
InChI
InChI=1S/C19H28Cl2N4O2/c1-24-17-9-8-15(25(12-10-20)13-11-21)14-16(17)22-18(24)6-4-2-3-5-7-19(26)23-27/h8-9,14,27H,2-7,10-13H2,1H3,(H,23,26)

Physicochemical Descriptors

Property Name Value
Molecular Formula C19H28Cl2N4O2
Molecular Weight 415.37
AlogP 3.86
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 12.0
Polar Surface Area 70.39
Molecular species NEUTRAL
Aromatic Rings 2.0
Heavy Atoms 27.0

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Melanoma 1 D008545 ClinicalTrials
Gliosarcoma 1 D018316 ClinicalTrials
Multiple Myeloma 1 D009101 ClinicalTrials

Cross References

Resources Reference
CAS NUMBER 1236199-60-2
ChEMBL CHEMBL3989941
DrugBank DB15147
FDA SRS 29DKI2H2NY
PubChem 46836227
SureChEMBL SCHEMBL7915449
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