Synonyms: | |
Status: | Approved (2016) |
Entry Type: | Small molecule |
Molecule Category: | Parent |
UNII: | KCU0C7RS7Z |
InChI Key | FHCUMDQMBHQXKK-CDIODLITSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C49H54N8O8 |
Molecular Weight | 883.02 |
AlogP | 7.73 |
Hydrogen Bond Acceptor | 10.0 |
Hydrogen Bond Donor | 4.0 |
Number of Rotational Bond | 11.0 |
Polar Surface Area | 193.1 |
Molecular species | NEUTRAL |
Aromatic Rings | 6.0 |
Heavy Atoms | 65.0 |
Action | Mechanism of Action | Reference |
---|---|---|
INHIBITOR | Nonstructural protein 5A inhibitor | FDA |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Unclassified protein
|
0-9 | - | - | - | - |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Hepatitis C, Chronic | 4 | D019698 | ClinicalTrials |
Hepatitis C | 2 | D006526 | ClinicalTrials |
Resources | Reference |
---|---|
CAS NUMBER | 1377049-84-7 |
ChEBI | 133009 |
ChEMBL | CHEMBL3545062 |
DrugBank | DB11613 |
DrugCentral | 5154 |
FDA SRS | KCU0C7RS7Z |
Guide to Pharmacology | 11269 |
PharmGKB | PA166163415 |
PubChem | 67683363 |
SureChEMBL | SCHEMBL8756902 |
ZINC | ZINC000203686879 |