Synonyms:
Status: Phase 2
Entry Type: Antibody
Molecule Category: UNKNOWN
UNII: 496K5Z02NW

Pharmacology

Action Mechanism of Action Reference
ANTAGONIST Integrin alpha-5/beta-1 antagonist PubMed PubMed
Primary Target
integrin α5β1
integrin, alpha 5 subunit (fibronectin receptor, alpha polypeptide)

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Ovarian Neoplasms 2 D010051 ClinicalTrials
Lung Neoplasms 2 D008175 ClinicalTrials
Pancreatic Neoplasms 2 D010190 ClinicalTrials
Melanoma 2 D008545 ClinicalTrials
Peritoneal Neoplasms 2 D010534 ClinicalTrials
Carcinoma, Non-Small-Cell Lung 1 D002289 ClinicalTrials
Macular Degeneration 1 D008268 ClinicalTrials

Cross References

Resources Reference
CAS NUMBER 558480-40-3
ChEMBL CHEMBL2108061
FDA SRS 496K5Z02NW
Guide to Pharmacology 10236