Synonyms: | |
Status: | Approved (2015) |
Entry Type: | Small molecule |
Molecule Category: | UNKNOWN Prodrug |
ATC: | J05AF13 |
UNII: | J4414G3BUK |
InChI Key | LDEKQSIMHVQZJK-CAQYMETFSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C21H29N6O5P |
Molecular Weight | 476.47 |
AlogP | 2.97 |
Hydrogen Bond Acceptor | 10.0 |
Hydrogen Bond Donor | 2.0 |
Number of Rotational Bond | 11.0 |
Polar Surface Area | 143.48 |
Molecular species | NEUTRAL |
Aromatic Rings | 3.0 |
Heavy Atoms | 33.0 |
Action | Mechanism of Action | Reference |
---|---|---|
INHIBITOR | Human immunodeficiency virus type 1 reverse transcriptase inhibitor | FDA |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Hepatitis B, Chronic | 3 | D019694 | ClinicalTrials |
HIV Infections | 3 | D015658 | ClinicalTrials |
Acquired Immunodeficiency Syndrome | 3 | D000163 | ClinicalTrials |
HIV Infections | 3 | D015658 | ClinicalTrials |
Hepatitis B, Chronic | 3 | D019694 | ClinicalTrials |
Severe Acute Respiratory Syndrome | 3 | D045169 | ClinicalTrials |
Leukemia, Lymphocytic, Chronic, B-Cell | 2 | D015451 | ClinicalTrials |
Hepatitis D | 2 | D003699 | ClinicalTrials |
Insulin Resistance | 1 | D007333 | ClinicalTrials |
Amyotrophic Lateral Sclerosis | 1 | D000690 | ClinicalTrials |
Resources | Reference |
---|---|
CAS NUMBER | 379270-37-8 |
ChEBI | 90926 |
ChEMBL | CHEMBL2107825 |
DrugBank | DB09299 |
DrugCentral | 4944 |
FDA SRS | J4414G3BUK |
PubChem | 9574767 |
SureChEMBL | SCHEMBL3107149 |
ZINC | ZINC000100055899 |