| Synonyms: | |
| Status: | Phase 1 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | 8O59X1ACZT |
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C19H14F3N3O3 |
| Molecular Weight | 389.33 |
| AlogP | 2.86 |
| Hydrogen Bond Acceptor | 4.0 |
| Hydrogen Bond Donor | 1.0 |
| Number of Rotational Bond | 3.0 |
| Polar Surface Area | 84.64 |
| Molecular species | None |
| Aromatic Rings | 2.0 |
| Heavy Atoms | 28.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
Transferase
|
- | - | - | - | 19.15 | |
|
Epigenetic regulator
Eraser
Histone deacetylase
HDAC class IIb
|
- | - | - | - | -5.44-16.76 |
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL3545417 |
| FDA SRS | 8O59X1ACZT |
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