OC000459

Search structure
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 04XB9TB8OL

Structure
InChI Key FATGTHLOZSXOBC-UHFFFAOYSA-N
Smile Cc1c(Cc2ccc3ccccc3n2)c2cc(F)ccc2n1CC(=O)O
InChI
InChI=1S/C21H17FN2O2/c1-13-17(11-16-8-6-14-4-2-3-5-19(14)23-16)18-10-15(22)7-9-20(18)24(13)12-21(25)26/h2-10H,11-12H2,1H3,(H,25,26)

Physicochemical Descriptors

Property Name Value
Molecular Formula C21H17FN2O2
Molecular Weight 348.38
AlogP 4.31
Hydrogen Bond Acceptor 3.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 4.0
Polar Surface Area 55.12
Molecular species ACID
Aromatic Rings 4.0
Heavy Atoms 26.0

Indications

Mesh Heading Maximum Phase Reference
Rhinitis; Rhinitis, Allergic Phase 2 ClinicalTrials
Asthma Phase 2 ClinicalTrials
Asthma; Common Cold; Picornaviridae Infections Phase 2 ClinicalTrials
Eosinophilic Esophagitis; Esophagitis Phase 2 ClinicalTrials
Dermatitis; Dermatitis, Atopic; Eczema Phase 2 ClinicalTrials
Asthma; Inflammation; Pulmonary Eosinophilia Phase 2 ClinicalTrials
Rhinitis; Rhinitis, Allergic Phase 2 ClinicalTrials
Asthma Phase 2 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL560993
DrugBank DB11900
EPA CompTox DTXSID00234343
FDA SRS 04XB9TB8OL
Guide to Pharmacology 9277
PubChem 11462174
SureChEMBL SCHEMBL1782956
ZINC ZINC000043120334
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