TESOFENSINE

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: BLH9UKX9V1

Structure
InChI Key VCVWXKKWDOJNIT-ZOMKSWQUSA-N
Smile CCOC[C@@H]1[C@@H](c2ccc(Cl)c(Cl)c2)C[C@@H]2CC[C@H]1N2C
InChI
InChI=1S/C17H23Cl2NO/c1-3-21-10-14-13(9-12-5-7-17(14)20(12)2)11-4-6-15(18)16(19)8-11/h4,6,8,12-14,17H,3,5,7,9-10H2,1-2H3/t12-,13+,14+,17+/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C17H23Cl2NO
Molecular Weight 328.28
AlogP 4.6
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 0.0
Number of Rotational Bond 4.0
Polar Surface Area 12.47
Molecular species BASE
Aromatic Rings 1.0
Heavy Atoms 21.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Monoamine transporter inhibitor PubMed PubMed PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Alzheimer Disease 2 D000544 ClinicalTrials
Obesity 2 D009765 ClinicalTrials
Diabetes Mellitus, Type 2 2 D003924 ClinicalTrials
Parkinson Disease 2 D010300 ClinicalTrials
Prader-Willi Syndrome 2 D011218 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
CAS NUMBER 195875-84-4
ChEMBL CHEMBL3989690
DrugBank DB06156
FDA SRS BLH9UKX9V1
PubChem 11370864
SureChEMBL SCHEMBL37509
ZINC ZINC000003953158
CONTENTS