D-MANNOSE

Search structure
Synonyms:
Status: Approved
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: PHA4727WTP

Structure
InChI Key WQZGKKKJIJFFOK-QTVWNMPRSA-N
Smile OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O
InChI
InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6?/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C6H12O6
Molecular Weight 180.16
AlogP -3.22
Hydrogen Bond Acceptor 6.0
Hydrogen Bond Donor 5.0
Number of Rotational Bond 1.0
Polar Surface Area 110.38
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 12.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Protease Serine protease Serine protease PA clan Serine protease S1A subfamily
- - - - 48-60
Other cytosolic protein
- - 2300 - -
Unclassified protein
- 10800 5150 - -

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Urinary Tract Infections 2 D014552 ClinicalTrials
Congenital Disorders of Glycosylation 1 D018981 ClinicalTrials

Related Entries

MCS

Cross References

Resources Reference
ChEBI 4208
ChEMBL CHEMBL469448
EPA CompTox DTXSID5040463
FDA SRS PHA4727WTP
Human Metabolome Database HMDB0000169
Guide to Pharmacology 4650
KEGG C00159
SureChEMBL SCHEMBL38300
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