SULBACTAM

Search structure
Synonyms:
Status: Approved (1986)
Entry Type: Small molecule
Molecule Category: Parent
ATC: J01CG01
UNII: S4TF6I2330

Structure
InChI Key FKENQMMABCRJMK-RITPCOANSA-N
Smile CC1(C)[C@H](C(=O)O)N2C(=O)C[C@H]2S1(=O)=O
InChI
InChI=1S/C8H11NO5S/c1-8(2)6(7(11)12)9-4(10)3-5(9)15(8,13)14/h5-6H,3H2,1-2H3,(H,11,12)/t5-,6+/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C8H11NO5S
Molecular Weight 233.25
AlogP -0.79
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 1.0
Polar Surface Area 91.75
Molecular species ACID
Aromatic Rings 0.0
Heavy Atoms 15.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Hydrolase
- 800-320000 - 167000 2-77
Enzyme Transferase
- - - - 7.736-13.47
Epigenetic regulator Eraser Histone deacetylase HDAC class IIb
- - - - -11.71--6.63

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Infections 3 D007239 ClinicalTrials
Urinary Tract Infections 3 D014552 ClinicalTrials
Cleft Palate 2 D002972 ClinicalTrials
Chorioamnionitis 2 D002821 ClinicalTrials
Osteomyelitis 1 D010019 ClinicalTrials

Related Entries

Scaffolds

Salt

Cross References

Resources Reference
CAS NUMBER 68373-14-8
ChEBI 9321
ChEMBL CHEMBL403
DrugBank DB09324
DrugCentral 2492
EPA CompTox DTXSID1023605
FDA SRS S4TF6I2330
Guide to Pharmacology 10769
KEGG C07770
PDB 0RN
PubChem 130313
SureChEMBL SCHEMBL47781
ZINC ZINC000000897244
CONTENTS