DEXAMETHASONE PHOSPHORIC ACID

Search structure
Synonyms:
Status: Approved (1959)
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 2BP70L44PR

Structure
InChI Key VQODGRNSFPNSQE-CXSFZGCWSA-N
Smile C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COP(=O)(O)O
InChI
InChI=1S/C22H30FO8P/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30)/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C22H30FO8P
Molecular Weight 472.45
AlogP 2.01
Hydrogen Bond Acceptor 6.0
Hydrogen Bond Donor 4.0
Number of Rotational Bond 4.0
Polar Surface Area 141.36
Molecular species ACID
Aromatic Rings 0.0
Heavy Atoms 32.0

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Uveitis, Anterior 3 D014606 ClinicalTrials
Dry Eye Syndromes 3 D015352 ClinicalTrials
Cataract 3 D002386 ClinicalTrials
Scleritis 1 D015423 ClinicalTrials
Macular Edema 1 D008269 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEBI 68637
ChEMBL CHEMBL1201302
DrugCentral 3920
EPA CompTox DTXSID2047430
FDA SRS 2BP70L44PR
PDB 3T5
PubChem 9400
SureChEMBL SCHEMBL135283
ZINC ZINC000003876071
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