RAZUPROTAFIB

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 0WAX4UT396

Structure
InChI Key KWJDHELCGJFUHW-SFTDATJTSA-N
Smile COC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(NS(=O)(=O)O)cc1)c1csc(-c2cccs2)n1
InChI
InChI=1S/C26H26N4O6S3/c1-36-26(32)29-21(15-17-6-3-2-4-7-17)24(31)27-20(22-16-38-25(28-22)23-8-5-13-37-23)14-18-9-11-19(12-10-18)30-39(33,34)35/h2-13,16,20-21,30H,14-15H2,1H3,(H,27,31)(H,29,32)(H,33,34,35)/t20-,21-/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C26H26N4O6S3
Molecular Weight 586.72
AlogP 4.45
Hydrogen Bond Acceptor 8.0
Hydrogen Bond Donor 4.0
Number of Rotational Bond 11.0
Polar Surface Area 146.72
Molecular species ACID
Aromatic Rings 4.0
Heavy Atoms 39.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Receptor-type tyrosine-protein phosphatase beta inhibitor PubMed PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Retinal Vein Occlusion 2 D012170 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL3931971
DrugBank DB16353
FDA SRS 0WAX4UT396
PubChem 46700782
SureChEMBL SCHEMBL679459
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