Synonyms: | |
Status: | Approved |
Entry Type: | Small molecule |
Molecule Category: | UNKNOWN |
ATC: | C08EX01 |
UNII: | J4ZHN3HBTE |
InChI Key | ZBIAKUMOEKILTF-UHFFFAOYSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C30H35F2N3O |
Molecular Weight | 491.63 |
AlogP | 5.75 |
Hydrogen Bond Acceptor | 3.0 |
Hydrogen Bond Donor | 1.0 |
Number of Rotational Bond | 9.0 |
Polar Surface Area | 35.58 |
Molecular species | NEUTRAL |
Aromatic Rings | 3.0 |
Heavy Atoms | 36.0 |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Ion channel
Voltage-gated ion channel
Potassium channels
Voltage-gated potassium channel
|
- | 16-16 | - | - | - | |
Ion channel
Voltage-gated ion channel
Voltage-gated sodium channel
|
- | 2400 | - | 77 | - | |
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC28 and SLC29 families of nucleoside transporters
SLC29 Facilitative nucleoside transporter family
|
- | 4954 | - | 280 | 90 |
Resources | Reference |
---|---|
ChEBI | 93095 |
ChEMBL | CHEMBL92870 |
DrugBank | DB13766 |
DrugCentral | 1580 |
EPA CompTox | DTXSID6045377 |
FDA SRS | J4ZHN3HBTE |
PharmGKB | PA165818137 |
PubChem | 3926 |
SureChEMBL | SCHEMBL79037 |
ZINC | ZINC000022034381 |