| Synonyms: | |
| Status: | Approved (2020) |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| ATC: | L01EX19 |
| UNII: | 9XW757O13D |
Structure
| InChI Key | CEFJVGZHQAGLHS-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C24H21BrFN5O2 |
| Molecular Weight | 510.37 |
| AlogP | 5.67 |
| Hydrogen Bond Acceptor | 5.0 |
| Hydrogen Bond Donor | 3.0 |
| Number of Rotational Bond | 5.0 |
| Polar Surface Area | 88.05 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 4.0 |
| Heavy Atoms | 33.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| INHIBITOR | Platelet-derived growth factor receptor alpha inhibitor | FDA |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Gastrointestinal Stromal Tumors | 4 | D046152 | ClinicalTrials |
Related Entries
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL4216467 |
| DrugBank | DB14840 |
| FDA SRS | 9XW757O13D |
| Guide to Pharmacology | 9175 |
| PubChem | 71584930 |
| SureChEMBL | SCHEMBL14999718 |
CONTENTS