ABX-464

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 26RU378B9V

Structure
InChI Key OZOGDCZJYVSUBR-UHFFFAOYSA-N
Smile FC(F)(F)Oc1ccc(Nc2ccc3cccc(Cl)c3n2)cc1
InChI
InChI=1S/C16H10ClF3N2O/c17-13-3-1-2-10-4-9-14(22-15(10)13)21-11-5-7-12(8-6-11)23-16(18,19)20/h1-9H,(H,21,22)

Physicochemical Descriptors

Property Name Value
Molecular Formula C16H10ClF3N2O
Molecular Weight 338.72
AlogP 5.53
Hydrogen Bond Acceptor 3.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 3.0
Polar Surface Area 34.15
Molecular species NEUTRAL
Aromatic Rings 3.0
Heavy Atoms 23.0

Pharmacology

Action Mechanism of Action Reference
MODULATOR Cap binding complex modulator PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Crohn Disease 2 D003424 ClinicalTrials
Arthritis, Rheumatoid 2 D001172 ClinicalTrials
Colitis, Ulcerative 2 D003093 ClinicalTrials
HIV Infections 2 D015658 ClinicalTrials
Severe Acute Respiratory Syndrome 2 D045169 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL4297344
DrugBank DB14828
FDA SRS 26RU378B9V
PubChem 49846599
SureChEMBL SCHEMBL1705888
CONTENTS