ANTAZOLINE PHOSPHATE

Search structure
Synonyms:
Status: Approved (1994)
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: VPR5FPH326

Structure
InChI Key DUIGUKRYYAGJAF-UHFFFAOYSA-N
Smile O=P(O)(O)O.c1ccc(CN(CC2=NCCN2)c2ccccc2)cc1
InChI
InChI=1S/C17H19N3.H3O4P/c1-3-7-15(8-4-1)13-20(14-17-18-11-12-19-17)16-9-5-2-6-10-16;1-5(2,3)4/h1-10H,11-14H2,(H,18,19);(H3,1,2,3,4)

Physicochemical Descriptors

Property Name Value
Molecular Formula C17H22N3O4P
Molecular Weight 363.35
AlogP 2.69
Hydrogen Bond Acceptor 3.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 5.0
Polar Surface Area 27.63
Molecular species BASE
Aromatic Rings 2.0
Heavy Atoms 20.0

Pharmacology

Action Mechanism of Action Reference
ANTAGONIST Histamine H1 receptor antagonist PubMed Wikipedia
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides
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Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL1200550
EPA CompTox DTXSID00165507
FDA SRS VPR5FPH326
PubChem 158798
SureChEMBL SCHEMBL23316
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