| Synonyms: | |
| Status: | Approved (2013) |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | 0F3M7032P5 |
Structure
| InChI Key | VVECGOCJFKTUAX-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C14H11FN2OS |
| Molecular Weight | 274.32 |
| AlogP | 3.85 |
| Hydrogen Bond Acceptor | 4.0 |
| Hydrogen Bond Donor | 2.0 |
| Number of Rotational Bond | 2.0 |
| Polar Surface Area | 45.15 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 3.0 |
| Heavy Atoms | 19.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Membrane receptor
|
- | 24 | - | 1 | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Alzheimer Disease | 2 | D000544 | ClinicalTrials |
Related Entries
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL579205 |
| DrugBank | DB15058 |
| FDA SRS | 0F3M7032P5 |
| PubChem | 10107393 |
| SureChEMBL | SCHEMBL10032130 |
| ZINC | ZINC000034220093 |
CONTENTS