SULFACETAMIDE

Search structure
Synonyms:
Status: Approved (1945)
Entry Type: Small molecule
Molecule Category: Parent
ATC: D10AF06
UNII: 4965G3J0F5

Structure
InChI Key SKIVFJLNDNKQPD-UHFFFAOYSA-N
Smile CC(=O)NS(=O)(=O)c1ccc(N)cc1
InChI
InChI=1S/C8H10N2O3S/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8/h2-5H,9H2,1H3,(H,10,11)

Physicochemical Descriptors

Property Name Value
Molecular Formula C8H10N2O3S
Molecular Weight 214.25
AlogP 0.09
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 2.0
Polar Surface Area 89.26
Molecular species ACID
Aromatic Rings 1.0
Heavy Atoms 14.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Bacterial dihydropteroate synthase inhibitor KEGG PubMed PubMed
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Oxidoreductase
- 18000 - - -
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC47 family of multidrug and toxin extrusion transporters
- - - - 80

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Osteomyelitis 0 D010019 ClinicalTrials

Cross References

Resources Reference
ChEBI 63845
ChEMBL CHEMBL455
DrugBank DB00634
DrugCentral 2497
EPA CompTox DTXSID8026060
FDA SRS 4965G3J0F5
Human Metabolome Database HMDB0014772
PharmGKB PA451536
PubChem 5320
SureChEMBL SCHEMBL40863
ZINC ZINC000005179119
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