TABIMORELIN

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: L51CBE03KF

Structure
InChI Key WURGZWOTGMLDJP-ZCYANPAGSA-N
Smile CNC(=O)[C@@H](Cc1ccccc1)N(C)C(=O)[C@@H](Cc1ccc2ccccc2c1)N(C)C(=O)/C=C/CC(C)(C)N
InChI
InChI=1S/C32H40N4O3/c1-32(2,33)19-11-16-29(37)35(4)28(22-24-17-18-25-14-9-10-15-26(25)20-24)31(39)36(5)27(30(38)34-3)21-23-12-7-6-8-13-23/h6-18,20,27-28H,19,21-22,33H2,1-5H3,(H,34,38)/b16-11+/t27-,28-/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C32H40N4O3
Molecular Weight 528.7
AlogP 3.71
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 11.0
Polar Surface Area 95.74
Molecular species BASE
Aromatic Rings 3.0
Heavy Atoms 39.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Cytochrome P450 3A4 inhibitor PubMed Wikipedia
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Membrane receptor Family A G protein-coupled receptor Peptide receptor (family A GPCR) Short peptide receptor (family A GPCR) GRP-related receptor
3-3 - - - -

Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL281764
FDA SRS L51CBE03KF
PubChem 9810101
SureChEMBL SCHEMBL209441
ZINC ZINC000003952532
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