| Synonyms: | |
| Status: | Phase 2 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | WM5Z385K7T |
Structure
| InChI Key | CWRVKFFCRWGWCS-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C6H10N4 |
| Molecular Weight | 138.17 |
| AlogP | 0.4 |
| Hydrogen Bond Acceptor | 4.0 |
| Hydrogen Bond Donor | 0.0 |
| Number of Rotational Bond | 0.0 |
| Polar Surface Area | 43.6 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 1.0 |
| Heavy Atoms | 10.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
Hydrolase
|
- | - | - | - | 2.024 | |
|
Enzyme
Transferase
|
- | - | - | - | 15.63 | |
|
Epigenetic regulator
Eraser
Histone deacetylase
HDAC class IIb
|
- | - | - | - | -21.54--15.58 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Idiopathic Hypersomnia | 2 | D020177 | ClinicalTrials |
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 34910 |
| ChEMBL | CHEMBL116943 |
| DrugBank | DB13415 |
| DrugCentral | 3428 |
| EPA CompTox | DTXSID7041091 |
| FDA SRS | WM5Z385K7T |
| KEGG | C13692 |
| PubChem | 5917 |
| SureChEMBL | SCHEMBL22674 |
| ZINC | ZINC000000001905 |
CONTENTS