ROSIPTOR

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 6R5034F862

Structure
InChI Key MDEJTPWQNNMAQF-BVMLLJBZSA-N
Smile C=C1CC[C@H]2[C@H](CN)[C@@H]([C@@]3(C)CC[C@H](O)C[C@@H]3CO)CC[C@]12C
InChI
InChI=1S/C20H35NO2/c1-13-4-5-17-16(11-21)18(7-9-19(13,17)2)20(3)8-6-15(23)10-14(20)12-22/h14-18,22-23H,1,4-12,21H2,2-3H3/t14-,15+,16+,17+,18+,19-,20+/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C20H35NO2
Molecular Weight 321.5
AlogP 3.1
Hydrogen Bond Acceptor 3.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 3.0
Polar Surface Area 66.48
Molecular species BASE
Aromatic Rings 0.0
Heavy Atoms 23.0

Pharmacology

Action Mechanism of Action Reference
ACTIVATOR Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 activator PubMed Other

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Cystitis, Interstitial 3 D018856 ClinicalTrials
Cystitis, Interstitial 3 D018856 ClinicalTrials
Dermatitis, Atopic 2 D003876 ClinicalTrials
Pulmonary Disease, Chronic Obstructive 2 D029424 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL3989954
DrugBank DB13012
FDA SRS 6R5034F862
Guide to Pharmacology 9249
PubChem 76965484
SureChEMBL SCHEMBL16055992
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