T-900607

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: IC9O2HT1X1

Structure
InChI Key FSXLOWIFSZNIMV-UHFFFAOYSA-N
Smile COc1ccc(NS(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)cc1NC(N)=O
InChI
InChI=1S/C14H10F5N3O4S/c1-26-7-3-2-5(4-6(7)21-14(20)23)22-27(24,25)13-11(18)9(16)8(15)10(17)12(13)19/h2-4,22H,1H3,(H3,20,21,23)

Physicochemical Descriptors

Property Name Value
Molecular Formula C14H10F5N3O4S
Molecular Weight 411.31
AlogP 2.68
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 5.0
Polar Surface Area 110.52
Molecular species ACID
Aromatic Rings 2.0
Heavy Atoms 27.0

Pharmacology

Action Mechanism of Action Reference
DISRUPTING AGENT Tubulin disrupting agent PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Carcinoma, Hepatocellular 2 D006528 ClinicalTrials
Ovarian Neoplasms 2 D010051 ClinicalTrials
Lymphoma, Non-Hodgkin 2 D008228 ClinicalTrials
Stomach Neoplasms 2 D013274 ClinicalTrials
Liver Neoplasms 2 D008113 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL4297440
DrugBank DB12068
FDA SRS IC9O2HT1X1
PubChem 9812416
SureChEMBL SCHEMBL2385373
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