SERINE

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 452VLY9402

Structure
InChI Key MTCFGRXMJLQNBG-REOHCLBHSA-N
Smile N[C@@H](CO)C(=O)O
InChI
InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C3H7NO3
Molecular Weight 105.09
AlogP -1.61
Hydrogen Bond Acceptor 3.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 2.0
Polar Surface Area 83.55
Molecular species ZWITTERION
Aromatic Rings 0.0
Heavy Atoms 7.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Hydrolase
- 15 - - -
Enzyme
- 15 - 50000 -

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Amyotrophic Lateral Sclerosis 2 D000690 ClinicalTrials
Stress Disorders, Post-Traumatic 2 D013313 ClinicalTrials
Pancreatic Neoplasms 2 D010190 ClinicalTrials
Alzheimer Disease 2 D000544 ClinicalTrials
Schizophrenia 2 D012559 ClinicalTrials
Psychotic Disorders 2 D011618 ClinicalTrials
Hereditary Sensory and Autonomic Neuropathies 1 D009477 ClinicalTrials

Cross References

Resources Reference
ChEBI 33384
ChEMBL CHEMBL11298
DrugBank DB00133
DrugCentral 4127
EPA CompTox DTXSID60883230
FDA SRS 452VLY9402
Human Metabolome Database HMDB0000187
Guide to Pharmacology 726
KEGG C00065
PDB SER
PharmGKB PA451330
PubChem 5951
SureChEMBL SCHEMBL1775
ZINC ZINC000000895034
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