ASP-3026

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Synonyms:	Asp 3026 Asp-3026 ASP3026
Status:	Phase 1
Entry Type:	Small molecule
Molecule Category:	UNKNOWN
UNII:	HP4L6MXF10

Structure


InChI Key	MGGBYMDAPCCKCT-UHFFFAOYSA-N
Smile	COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncnc(Nc2ccccc2S(=O)(=O)C(C)C)n1
InChI	InChI=1S/C29H40N8O3S/c1-21(2)41(38,39)27-8-6-5-7-25(27)33-29-31-20-30-28(34-29)32-24-10-9-23(19-26(24)40-4)36-13-11-22(12-14-36)37-17-15-35(3)16-18-37/h5-10,19-22H,11-18H2,1-4H3,(H2,30,31,32,33,34)

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C29H40N8O3S
Molecular Weight	580.76
AlogP	3.77
Hydrogen Bond Acceptor	11.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	9.0
Polar Surface Area	115.82
Molecular species	NEUTRAL
Aromatic Rings	3.0
Heavy Atoms	41.0

Pharmacology

Action	Mechanism of Action	Reference
INHIBITOR	ALK tyrosine kinase receptor inhibitor	PubMed

Indications

Mesh Heading	Maximum Phase	Mesh ID	Reference
Lymphoma, Follicular	1	D008224	ClinicalTrials
Neoplasms	1	D009369	ClinicalTrials
Neoplasms	1	D009369	ClinicalTrials

Cross References

Resources	Reference
ChEBI	167650
ChEMBL	CHEMBL3545360
DrugBank	DB12729
EPA CompTox	DTXSID90149038
FDA SRS	HP4L6MXF10
Guide to Pharmacology	7740
PDB	F6O
PubChem	25134326
SureChEMBL	SCHEMBL2827739
ZINC	ZINC000068120928

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