TECALCET HYDROCHLORIDE

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 3HP28R98LC

Structure
InChI Key YJXUXANREVNZLH-PFEQFJNWSA-N
Smile COc1cccc([C@@H](C)NCCCc2ccccc2Cl)c1.Cl
InChI
InChI=1S/C18H22ClNO.ClH/c1-14(16-8-5-10-17(13-16)21-2)20-12-6-9-15-7-3-4-11-18(15)19;/h3-5,7-8,10-11,13-14,20H,6,9,12H2,1-2H3;1H/t14-;/m1./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C18H23Cl2NO
Molecular Weight 340.29
AlogP 4.63
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 7.0
Polar Surface Area 21.26
Molecular species BASE
Aromatic Rings 2.0
Heavy Atoms 21.0

Pharmacology

Action Mechanism of Action Reference
MODULATOR Calcium sensing receptor modulator PubMed PubMed PubMed
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Membrane receptor Family C G protein-coupled receptor Ion receptor (family C GPCR) Calcium sensing receptor Calcium sensing receptor
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Cross References

Resources Reference
ChEMBL CHEMBL2107572
EPA CompTox DTXSID10170263
FDA SRS 3HP28R98LC
PubChem 158796
SureChEMBL SCHEMBL1178446
CONTENTS