PC-786

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: MC0MD9J0F4

Structure
InChI Key VTCJNYICQADBJD-UHFFFAOYSA-N
Smile Cc1cnc(N2CC3(CCOCC3)C2)c(C(=O)Nc2ccc(C(=O)N3CCc4cc(C(=O)Nc5c(C)cccc5F)sc4-c4ccccc43)cc2)c1
InChI
InChI=1S/C41H38FN5O4S/c1-25-20-31(37(43-22-25)46-23-41(24-46)15-18-51-19-16-41)38(48)44-29-12-10-27(11-13-29)40(50)47-17-14-28-21-34(52-36(28)30-7-3-4-9-33(30)47)39(49)45-35-26(2)6-5-8-32(35)42/h3-13,20-22H,14-19,23-24H2,1-2H3,(H,44,48)(H,45,49)

Physicochemical Descriptors

Property Name Value
Molecular Formula C41H38FN5O4S
Molecular Weight 715.85
AlogP 7.89
Hydrogen Bond Acceptor 7.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 6.0
Polar Surface Area 103.87
Molecular species NEUTRAL
Aromatic Rings 5.0
Heavy Atoms 52.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR RNA-directed RNA polymerase L inhibitor PubMed PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Respiratory Syncytial Virus Infections 2 D018357 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL4291143
FDA SRS MC0MD9J0F4
PubChem 121276461
SureChEMBL SCHEMBL17678723
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