IBERDOMIDE HYDROCHLORIDE

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 79L3645KFI

Structure
InChI Key VVHQVXXPZDALDV-BOXHHOBZSA-N
Smile Cl.O=C1CC[C@H](N2Cc3c(OCc4ccc(CN5CCOCC5)cc4)cccc3C2=O)C(=O)N1
InChI
InChI=1S/C25H27N3O5.ClH/c29-23-9-8-21(24(30)26-23)28-15-20-19(25(28)31)2-1-3-22(20)33-16-18-6-4-17(5-7-18)14-27-10-12-32-13-11-27;/h1-7,21H,8-16H2,(H,26,29,30);1H/t21-;/m0./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C25H28ClN3O5
Molecular Weight 485.97
AlogP 1.86
Hydrogen Bond Acceptor 6.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 6.0
Polar Surface Area 88.18
Molecular species NEUTRAL
Aromatic Rings 2.0
Heavy Atoms 33.0

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Smoldering Multiple Myeloma 2 D000075122 ClinicalTrials
Sarcoidosis 2 D012507 ClinicalTrials
Lupus Erythematosus, Systemic 2 D008180 ClinicalTrials
Multiple Myeloma 1 D009101 ClinicalTrials
Lymphoma 1 D008223 ClinicalTrials
Lymphoma, Non-Hodgkin 1 D008228 ClinicalTrials
Lymphoma, Follicular 1 D008224 ClinicalTrials
Liver Diseases 1 D008107 ClinicalTrials
Lymphoma, Large B-Cell, Diffuse 1 D016403 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL3989912
FDA SRS 79L3645KFI
PubChem 72793904
SureChEMBL SCHEMBL15465936
CONTENTS