BROMPHENIRAMINE

Search structure
Synonyms:
BPN
Status: Approved (1957)
Entry Type: Small molecule
Molecule Category: Parent
ATC: R06AB01
UNII: H57G17P2FN

Structure
InChI Key ZDIGNSYAACHWNL-UHFFFAOYSA-N
Smile CN(C)CCC(c1ccc(Br)cc1)c1ccccn1
InChI
InChI=1S/C16H19BrN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3

Physicochemical Descriptors

Property Name Value
Molecular Formula C16H19BrN2
Molecular Weight 319.25
AlogP 3.93
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 0.0
Number of Rotational Bond 5.0
Polar Surface Area 16.13
Molecular species BASE
Aromatic Rings 2.0
Heavy Atoms 19.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Ion channel Voltage-gated ion channel Potassium channels Voltage-gated potassium channel
- 891 - - -
Ion channel Voltage-gated ion channel Voltage-gated calcium channel
- 16120 - - -
Ion channel Voltage-gated ion channel Voltage-gated sodium channel
- 11000-16000 - - 44-46
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC06 neurotransmitter transporter family
- 300 - - -

Indications

Mesh Heading Maximum Phase Mesh ID Reference

Related Entries

Scaffolds

Cross References

Resources Reference
ChEBI 3183
ChEMBL CHEMBL811
DrugBank DB00835
DrugCentral 408
EPA CompTox DTXSID5022691
FDA SRS H57G17P2FN
Human Metabolome Database HMDB0001941
Guide to Pharmacology 7133
KEGG C06857
PharmGKB PA448675
PubChem 6834
SureChEMBL SCHEMBL4814
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