Synonyms: | |
Status: | Phase 2 |
Entry Type: | Small molecule |
Molecule Category: | UNKNOWN |
UNII: | ZB05V621UD |
InChI Key | LYXKFNHUJJDTIA-UHFFFAOYSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C23H26ClN3O5S |
Molecular Weight | 492.0 |
AlogP | 2.86 |
Hydrogen Bond Acceptor | 7.0 |
Hydrogen Bond Donor | 0.0 |
Number of Rotational Bond | 6.0 |
Polar Surface Area | 79.39 |
Molecular species | NEUTRAL |
Aromatic Rings | 2.0 |
Heavy Atoms | 33.0 |
Action | Mechanism of Action | Reference |
---|---|---|
ANTAGONIST | Serotonin 1a (5-HT1a) receptor antagonist | PubMed |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Membrane receptor
Family A G protein-coupled receptor
Small molecule receptor (family A GPCR)
Monoamine receptor
Serotonin receptor
|
- | - | 0-0 | 1 | - |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Depressive Disorder | 2 | D003866 | ClinicalTrials |
Resources | Reference |
---|---|
ChEMBL | CHEMBL79261 |
DrugBank | DB16040 |
EPA CompTox | DTXSID00167208 |
FDA SRS | ZB05V621UD |
SureChEMBL | SCHEMBL1082516 |