TETRAHYDROZOLINE

Search structure
Synonyms:
Status: Approved (1979)
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: P7M4KML3S8

Structure
InChI Key BYJAVTDNIXVSPW-UHFFFAOYSA-N
Smile c1ccc2c(c1)CCCC2C1=NCCN1
InChI
InChI=1S/C13H16N2/c1-2-6-11-10(4-1)5-3-7-12(11)13-14-8-9-15-13/h1-2,4,6,12H,3,5,7-9H2,(H,14,15)

Physicochemical Descriptors

Property Name Value
Molecular Formula C13H16N2
Molecular Weight 200.28
AlogP 2.11
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 1.0
Polar Surface Area 24.39
Molecular species BASE
Aromatic Rings 1.0
Heavy Atoms 15.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Monoamine receptor Adrenergic receptor
- 1600 - 11 -

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Dry Eye Syndromes 0 D015352 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEBI 28674
ChEMBL CHEMBL1266
DrugBank DB06764
DrugCentral 3591
EPA CompTox DTXSID1047861
FDA SRS P7M4KML3S8
KEGG C07912
PubChem 5419
SureChEMBL SCHEMBL34760
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