ODELEPRAN

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 4VZT670SD9

Structure
InChI Key QWNDOCKIKKQJNN-UHFFFAOYSA-N
Smile NC(=O)c1ccc(Oc2ccc(CNCCC3CCOCC3)cc2F)nc1
InChI
InChI=1S/C20H24FN3O3/c21-17-11-15(12-23-8-5-14-6-9-26-10-7-14)1-3-18(17)27-19-4-2-16(13-24-19)20(22)25/h1-4,11,13-14,23H,5-10,12H2,(H2,22,25)

Physicochemical Descriptors

Property Name Value
Molecular Formula C20H24FN3O3
Molecular Weight 373.43
AlogP 3.02
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 8.0
Polar Surface Area 86.47
Molecular species BASE
Aromatic Rings 2.0
Heavy Atoms 27.0

Pharmacology

Action Mechanism of Action Reference
ANTAGONIST Opioid receptors; mu/kappa/delta antagonist PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Alcoholism 2 D000437 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL2103878
DrugBank DB12585
FDA SRS 4VZT670SD9
SureChEMBL SCHEMBL1533189
ZINC ZINC000038910715
CONTENTS