MEDRONIC ACID

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 73OS0QIN3O

Structure
InChI Key MBKDYNNUVRNNRF-UHFFFAOYSA-N
Smile O=P(O)(O)CP(=O)(O)O
InChI
InChI=1S/CH6O6P2/c2-8(3,4)1-9(5,6)7/h1H2,(H2,2,3,4)(H2,5,6,7)

Physicochemical Descriptors

Property Name Value
Molecular Formula CH6O6P2
Molecular Weight 176.0
AlogP -0.7
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 4.0
Number of Rotational Bond 2.0
Polar Surface Area 115.06
Molecular species ACID
Aromatic Rings 0.0
Heavy Atoms 9.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Hydrolase
- - - 3 -
Enzyme Lyase
- 1250000 - 1250000 -
Enzyme Phosphatase
- - - 140000 -
Enzyme Protease Metallo protease Metallo protease MAM clan Metallo protease M10A subfamily
- 49000 - - -
Enzyme Transferase
- - - 9000000 2.39-3.11
Epigenetic regulator Eraser Histone deacetylase HDAC class IIb
- - - - -13.18-18.33

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Renal Insufficiency, Chronic 3 D051436 ClinicalTrials
Osteogenesis Imperfecta 3 D010013 ClinicalTrials
Osteoporosis, Postmenopausal 2 D015663 ClinicalTrials

Cross References

Resources Reference
ChEBI 43945
ChEMBL CHEMBL180570
DrugBank DB14078
EPA CompTox DTXSID8045696
FDA SRS 73OS0QIN3O
PDB MDN
PubChem 16124
SureChEMBL SCHEMBL66716
ZINC ZINC000008015016
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