TENOFOVIR DISOPROXIL ASPARTATE

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: F06G7ZBB70

Structure
InChI Key CCIDLBRRXVNEDK-KJTVYDLOSA-N
Smile CC(C)OC(=O)OCOP(=O)(CO[C@H](C)Cn1cnc2c(N)ncnc21)OCOC(=O)OC(C)C.N[C@@H](CC(=O)O)C(=O)O
InChI
InChI=1S/C19H30N5O10P.C4H7NO4/c1-12(2)33-18(25)28-9-31-35(27,32-10-29-19(26)34-13(3)4)11-30-14(5)6-24-8-23-15-16(20)21-7-22-17(15)24;5-2(4(8)9)1-3(6)7/h7-8,12-14H,6,9-11H2,1-5H3,(H2,20,21,22);2H,1,5H2,(H,6,7)(H,8,9)/t14-;2-/m10/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C23H37N6O14P
Molecular Weight 652.55
AlogP 3.04
Hydrogen Bond Acceptor 15.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 13.0
Polar Surface Area 185.44
Molecular species NEUTRAL
Aromatic Rings 2.0
Heavy Atoms 35.0

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Hepatitis B, Chronic 3 D019694 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL4594453
FDA SRS F06G7ZBB70
PubChem 73291783
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