Synonyms: | |
Status: | Phase 2 |
Entry Type: | Protein |
Molecule Category: | UNKNOWN |
UNII: | 2MK663C346 |
InChI Key | IDXCXSCCZNCXCL-XMADEQCMSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C49H75N15O12S |
Molecular Weight | 1098.3 |
AlogP | None |
Hydrogen Bond Acceptor | None |
Hydrogen Bond Donor | None |
Number of Rotational Bond | None |
Polar Surface Area | None |
Molecular species | None |
Aromatic Rings | None |
Heavy Atoms | None |
Action | Mechanism of Action | Reference |
---|---|---|
AGONIST | Bradykinin B2 receptor agonist | PubMed |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Membrane receptor
Family A G protein-coupled receptor
Peptide receptor (family A GPCR)
Short peptide receptor (family A GPCR)
Bradykinin receptor
|
- | - | - | 19 | - |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Central Nervous System Neoplasms | 2 | D016543 | ClinicalTrials |
Medulloblastoma | 1 | D008527 | ClinicalTrials |
Meningitis, Cryptococcal | 1 | D016919 | ClinicalTrials |
Glioma | 1 | D005910 | ClinicalTrials |
Resources | Reference |
---|---|
ChEMBL | CHEMBL2105864 |
DrugBank | DB06549 |
FDA SRS | 2MK663C346 |
Guide to Pharmacology | 672 |
PubChem | 6918284 |
SureChEMBL | SCHEMBL411837 |