BAMOCAFTOR

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 8C7XEW3K7S

Structure
InChI Key IGEOJNMYRZUKIK-IBGZPJMESA-N
Smile C[C@@H]1CN(c2nc(-n3ccc(OCCC4(C(F)(F)F)CC4)n3)ccc2C(=O)NS(=O)(=O)c2ccccc2)C(C)(C)C1
InChI
InChI=1S/C28H32F3N5O4S/c1-19-17-26(2,3)35(18-19)24-21(25(37)34-41(38,39)20-7-5-4-6-8-20)9-10-22(32-24)36-15-11-23(33-36)40-16-14-27(12-13-27)28(29,30)31/h4-11,15,19H,12-14,16-18H2,1-3H3,(H,34,37)/t19-/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C28H32F3N5O4S
Molecular Weight 591.66
AlogP 5.12
Hydrogen Bond Acceptor 8.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 9.0
Polar Surface Area 106.42
Molecular species ACID
Aromatic Rings 3.0
Heavy Atoms 41.0

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Cystic Fibrosis 3 D003550 ClinicalTrials

Cross References

Resources Reference
ChEMBL CHEMBL4297849
DrugBank DB15177
FDA SRS 8C7XEW3K7S
Guide to Pharmacology 10553
PubChem 134393443
SureChEMBL SCHEMBL20023905
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