BROMOPRIDE

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
ATC: A03FA04
UNII: 75473V2YZK

Structure
InChI Key GIYAQDDTCWHPPL-UHFFFAOYSA-N
Smile CCN(CC)CCNC(=O)c1cc(Br)c(N)cc1OC
InChI
InChI=1S/C14H22BrN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19)

Physicochemical Descriptors

Property Name Value
Molecular Formula C14H22BrN3O2
Molecular Weight 344.25
AlogP 2.11
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 7.0
Polar Surface Area 67.59
Molecular species BASE
Aromatic Rings 1.0
Heavy Atoms 20.0

Pharmacology

Action Mechanism of Action Reference
ANTAGONIST Dopamine D2 receptor antagonist PubMed
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides
- - - - 86

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Dyspepsia 3 D004415 ClinicalTrials

Cross References

Resources Reference
ChEBI 95304
ChEMBL CHEMBL399510
DrugBank DB09018
DrugCentral 406
EPA CompTox DTXSID0045383
FDA SRS 75473V2YZK
PubChem 2446
SureChEMBL SCHEMBL54497
ZINC ZINC000002038104
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