DELAPRIL

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
ATC: C09AA12
UNII: W77UAL9THI

Structure
InChI Key WOUOLAUOZXOLJQ-MBSDFSHPSA-N
Smile CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N(CC(=O)O)C1Cc2ccccc2C1
InChI
InChI=1S/C26H32N2O5/c1-3-33-26(32)23(14-13-19-9-5-4-6-10-19)27-18(2)25(31)28(17-24(29)30)22-15-20-11-7-8-12-21(20)16-22/h4-12,18,22-23,27H,3,13-17H2,1-2H3,(H,29,30)/t18-,23-/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C26H32N2O5
Molecular Weight 452.55
AlogP 2.61
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 11.0
Polar Surface Area 95.94
Molecular species ACID
Aromatic Rings 2.0
Heavy Atoms 33.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Angiotensin-converting enzyme inhibitor PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Hypertension 3 D006973 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEBI 135735
ChEMBL CHEMBL589583
DrugBank DB13312
DrugCentral 798
FDA SRS W77UAL9THI
PubChem 5362116
SureChEMBL SCHEMBL34120
ZINC ZINC000003794599
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