LECOZOTAN HYDROCHLORIDE

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 23EDE20K1X

Structure
InChI Key GXYZREDEYDFJPT-ZMBIFBSDSA-N
Smile C[C@H](CN(C(=O)c1ccc(C#N)cc1)c1ccccn1)N1CCN(c2cccc3c2OCCO3)CC1.Cl
InChI
InChI=1S/C28H29N5O3.ClH/c1-21(31-13-15-32(16-14-31)24-5-4-6-25-27(24)36-18-17-35-25)20-33(26-7-2-3-12-30-26)28(34)23-10-8-22(19-29)9-11-23;/h2-12,21H,13-18,20H2,1H3;1H/t21-;/m1./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C28H30ClN5O3
Molecular Weight 520.03
AlogP 3.58
Hydrogen Bond Acceptor 7.0
Hydrogen Bond Donor 0.0
Number of Rotational Bond 6.0
Polar Surface Area 81.93
Molecular species NEUTRAL
Aromatic Rings 3.0
Heavy Atoms 36.0

Pharmacology

Action Mechanism of Action Reference
ANTAGONIST Serotonin 1a (5-HT1a) receptor antagonist PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Alzheimer Disease 2 D000544 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL2107349
EPA CompTox DTXSID20195826
FDA SRS 23EDE20K1X
PubChem 11156648
SureChEMBL SCHEMBL1036321
CONTENTS