| Synonyms: | |
| Status: | Phase 3 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | JXH6X663L0 |
Structure
| InChI Key | ZEYYDOLCHFETHQ-JOCHJYFZSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C23H23NO3 |
| Molecular Weight | 361.44 |
| AlogP | 5.17 |
| Hydrogen Bond Acceptor | 3.0 |
| Hydrogen Bond Donor | 1.0 |
| Number of Rotational Bond | 6.0 |
| Polar Surface Area | 59.42 |
| Molecular species | ACID |
| Aromatic Rings | 3.0 |
| Heavy Atoms | 27.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| INHIBITOR | 5-lipoxygenase activating protein inhibitor | PubMed |
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
Oxidoreductase
|
- | 60 | - | - | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Acute Coronary Syndrome | 3 | D054058 | ClinicalTrials |
Related Entries
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL88712 |
| DrugBank | DB16346 |
| EPA CompTox | DTXSID60155843 |
| FDA SRS | JXH6X663L0 |
| Guide to Pharmacology | 5148 |
| PDB | QY1 |
| PubChem | 123723 |
| SureChEMBL | SCHEMBL1004174 |
| ZINC | ZINC000000598193 |
CONTENTS