| Synonyms: | |
| Status: | Phase 3 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | 1K77H2Z9B1 |
Structure
| InChI Key | MTCFGRXMJLQNBG-UWTATZPHSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C3H7NO3 |
| Molecular Weight | 105.09 |
| AlogP | -1.61 |
| Hydrogen Bond Acceptor | 3.0 |
| Hydrogen Bond Donor | 3.0 |
| Number of Rotational Bond | 2.0 |
| Polar Surface Area | 83.55 |
| Molecular species | ZWITTERION |
| Aromatic Rings | 0.0 |
| Heavy Atoms | 7.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Ion channel
Ligand-gated ion channel
Ionotropic glutamate receptor
NMDA receptor
|
160-200 | 300 | - | 316 | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Schizophrenia | 3 | D012559 | ClinicalTrials |
| Psychotic Disorders | 3 | D011618 | ClinicalTrials |
| Cocaine-Related Disorders | 2 | D019970 | ClinicalTrials |
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 16523 |
| ChEMBL | CHEMBL285123 |
| DrugBank | DB03929 |
| EPA CompTox | DTXSID9041021 |
| FDA SRS | 1K77H2Z9B1 |
| Human Metabolome Database | HMDB0003406 |
| Guide to Pharmacology | 4171 |
| KEGG | C00740 |
| PDB | DSN |
| SureChEMBL | SCHEMBL43094 |
| ZINC | ZINC000000895342 |
CONTENTS