| Synonyms: | |
| Status: | Phase 2 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | 6I7PLF6N8L |
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C26H28FN5O |
| Molecular Weight | 445.54 |
| AlogP | 4.66 |
| Hydrogen Bond Acceptor | 4.0 |
| Hydrogen Bond Donor | 3.0 |
| Number of Rotational Bond | 5.0 |
| Polar Surface Area | 73.05 |
| Molecular species | None |
| Aromatic Rings | 3.0 |
| Heavy Atoms | 33.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| INHIBITOR | Fibroblast growth factor receptor inhibitor |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Carcinoma, Non-Small-Cell Lung | 2 | D002289 | ClinicalTrials |
| Carcinoma, Renal Cell | 2 | D002292 | ClinicalTrials |
| Multiple Myeloma | 2 | D009101 | ClinicalTrials |
| Leukemia, Myeloid, Acute | 2 | D015470 | ClinicalTrials |
| Ovarian Neoplasms | 2 | D010051 | ClinicalTrials |
| Colorectal Neoplasms | 2 | D015179 | ClinicalTrials |
| Neoplasms | 1 | D009369 | ClinicalTrials |
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL3545285 |
| FDA SRS | 6I7PLF6N8L |
| PubChem | 10433653 |
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