TETRAHYDROCANNABIVARIN

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: I5YE3I47D8

Structure
InChI Key ZROLHBHDLIHEMS-HUUCEWRRSA-N
Smile CCCc1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(C)=C[C@@H]21
InChI
InChI=1S/C19H26O2/c1-5-6-13-10-16(20)18-14-9-12(2)7-8-15(14)19(3,4)21-17(18)11-13/h9-11,14-15,20H,5-8H2,1-4H3/t14-,15-/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C19H26O2
Molecular Weight 286.42
AlogP 4.96
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 2.0
Polar Surface Area 29.46
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 21.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Lipid-like ligand receptor (family A GPCR) Cannabinoid receptor
- 13 - 2-75 -

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Diabetes Mellitus, Type 2 2 D003924 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL2387541
DrugBank DB11755
EPA CompTox DTXSID10893920
FDA SRS I5YE3I47D8
Guide to Pharmacology 6418
PubChem 93147
SureChEMBL SCHEMBL6856739
ZINC ZINC000005649505
CONTENTS