TEGLARINAD CHLORIDE

Search structure
Synonyms:
Status: Phase 1
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: D6V5QYX9MZ

Structure
InChI Key DAHMXVAETAAQOZ-UHFFFAOYSA-N
Smile COCCOCCOCCOCCOC(=O)OC[n+]1ccc(N/C(=N/CCCCCCOc2ccc(Cl)cc2)NC#N)cc1.[Cl-]
InChI
InChI=1S/C30H42ClN5O8.ClH/c1-38-16-17-39-18-19-40-20-21-41-22-23-43-30(37)44-25-36-13-10-27(11-14-36)35-29(34-24-32)33-12-4-2-3-5-15-42-28-8-6-26(31)7-9-28;/h6-11,13-14H,2-5,12,15-23,25H2,1H3,(H,33,34);1H

Physicochemical Descriptors

Property Name Value
Molecular Formula C30H43Cl2N5O8
Molecular Weight 672.61
AlogP 3.91
Hydrogen Bond Acceptor 10.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 23.0
Polar Surface Area 145.77
Molecular species NEUTRAL
Aromatic Rings 2.0
Heavy Atoms 44.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Nicotinamide phosphoribosyltransferase inhibitor PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Lymphoma 1 D008223 ClinicalTrials

Cross References

Resources Reference
ChEMBL CHEMBL190412
FDA SRS D6V5QYX9MZ
PubChem 9961434
SureChEMBL SCHEMBL2672343
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