| Synonyms: | |
| Status: | Phase 2 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | 2TM92XK3YA |
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C23H21F3N4O4 |
| Molecular Weight | 474.44 |
| AlogP | 3.87 |
| Hydrogen Bond Acceptor | 7.0 |
| Hydrogen Bond Donor | 2.0 |
| Number of Rotational Bond | 6.0 |
| Polar Surface Area | 96.81 |
| Molecular species | None |
| Aromatic Rings | 3.0 |
| Heavy Atoms | 34.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| ANTAGONIST | Vanilloid receptor antagonist |
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Ion channel
Voltage-gated ion channel
Transient receptor potential channel
|
- | 236 | - | - | - |
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL3545228 |
| FDA SRS | 2TM92XK3YA |
CONTENTS